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This 72-week multicenter, randomized, double-blind, placebo-controlled study included 320 middle-aged obese patients with biopsy-proven NASH (mean age: 55 years
Updated phase 3 titration pathway The phase 3 schedule uses the following escalation: Weeks 1-4: 2mg weekly Weeks 5-8: 4mg weekly Weeks 9-12: 8mg weekly Week 13+: Maintenance dose (4mg, 9mg, or 12mg depending on assignment) The introduction of a 9mg dose option is interesting
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